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Transmission of Malaria

Edexcel A-level BiologyViruses, Fungi and ProtozoaLesson 13 of 17

Malaria is not passed directly from person to person. It is transmitted by the bite of an infected female Anopheles mosquito, which needs a blood meal to develop her eggs. Male mosquitoes feed on nectar and do not transmit malaria.

Infection of the human
1. When an infected mosquito bites, it injects saliva containing sporozoites into the blood.
2. Within about 30 minutes the sporozoites reach the liver and enter liver cells.
3. In each liver cell a sporozoite divides asexually many times, producing thousands of merozoites. After one to two weeks the liver cell bursts, releasing them into the blood.

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Key terms in this lesson

sporozoite
The infective stage of the malaria parasite, injected into the blood by a mosquito bite, which invades liver cells.
merozoite
A stage of the malaria parasite produced by asexual division in liver cells or red blood cells, which goes on to invade further red blood cells.
gametocyte
A sexual stage of the malaria parasite that develops in the blood and is taken up by a mosquito to form gametes.

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