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Cell Differentiation

Edexcel A-level BiologyGene ExpressionLesson 14 of 39

Cell differentiation is the process by which an unspecialised cell becomes specialised to carry out a particular function. A human body contains over 200 different types of specialised cell, all produced from a single fertilised egg.

Differential gene expression
Almost all body cells contain the same genes, because they were all produced by mitosis from the zygote. Cells differentiate because they express different genes. In each cell type:
• some genes are switched on, so their mRNA is transcribed and the proteins are made
• other genes are switched off, so their proteins are not made.
The proteins made determine the structure and function of the cell. This is called differential gene expression.

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Key terms in this lesson

zygote
The single diploid cell formed by the fusion of a sperm and an egg at fertilisation.

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