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Amides

OCR A-level Organic ChemistryCarbon-Carbon Bond FormationLesson 7 of 8

An amide contains the group −CONH−: a carbonyl group, C=O, bonded directly to a nitrogen atom.

OCR recognises two types:

• a primary amide, RCONH2, where the nitrogen carries two hydrogen atoms, e.g. ethanamide, CH3CONH2
• a secondary amide, RCONHR', where one hydrogen on the nitrogen has been replaced by an alkyl (or aryl) group, e.g. CH3CONHCH3

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Key terms in this lesson

acyl chloride
A carboxylic acid derivative in which the -OH of the carboxyl group is replaced by -Cl.

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