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Comparing DNA

AQA AS-level BiologyBiodiversityLesson 16 of 33

DNA sequencing can now be done by machines so base sequences can be compared to establish relationships between species.

The Sanger method is used to sequence DNA fragments.

Modified nucleotides which can attach to a base but are terminators are used.

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Key terms in this lesson

nucleotide
A molecule made of a pentose sugar, a phosphate group and a nitrogen-containing base.
DNA polymerase
The enzyme that joins free nucleotides together to form a new complementary strand of DNA.
species
A group of organisms with similar characteristics that can interbreed to produce fertile offspring.

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