BRAINCAKE

Transmission of Impulse across Synapse

OCR A-level BiologyNeuronal CommunicationLesson 21 of 38

When an action potential reaches the pre-synaptic bulb, calcium ion channels open. The diffusion of calcium ions into the axon causes vesicles containing neurotransmitters to move to the pre-synaptic membrane, fuse with the membrane and release their contents by exocytosis.

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Key terms in this lesson

Action potential
The temporary reversal of the electrical charge across an axon membrane, from about -70mV to +40mV, that occurs when a neurone is stimulated above threshold.
Neurotransmitter
A chemical released from the presynaptic membrane at a synapse that diffuses across the synaptic cleft and binds to receptors on the postsynaptic membrane, triggering a response.

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