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Conditions of the Hardy Weinberg Equilibrium

Edexcel A-level BiologyGene PoolsLesson 5 of 16

The Hardy-Weinberg principle only predicts constant allele frequencies if certain conditions are met. These are the assumptions of the model:

• Large population: so that chance events (genetic drift) do not change allele frequencies.
• Random mating: every individual is equally likely to mate with any other, whatever its genotype.
• No mutation: no new alleles are created and existing alleles are not changed.
• No migration: no individuals, and so no alleles, move into or out of the population (no gene flow).
• No natural selection: all genotypes are equally likely to survive and reproduce.

The Hardy-Weinberg equations also assume the organism is diploid, reproduces sexually and has non-overlapping generations.

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Key terms in this lesson

allele frequency
The proportion of all the alleles of a gene in a population that are a particular allele.

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