Blood Clotting
If the skin is reached, the blood clots rapidly to seal the wound, prevent loss of blood and prevent pathogens from entering the body.
When platelets come into contact with collagen in the skin or the wall of damaged blood vessels, they are activated. Activated platelets change shape and stick to the walls of the damaged blood vessels.
Exposed collagen fibres release ATP and other inflammatory mediators to attract macrophages to the site.
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Key terms in this lesson
- ATP
- Adenosine triphosphate, a nucleotide that acts as the immediate energy source of a cell, releasing energy when hydrolysed to ADP and inorganic phosphate.
- pathogen
- A microorganism that causes disease.
More in Communicable Diseases
- Factors Affecting Transmission in Animals
- Transmission of Pathogens Between Plants
- Plant Defences against Pathogens
- Mammals - non-Specific Defences
- Inflammatory Response
- Fevers
- Phagocytosis
- Counting Blood Cells
All 40 lessons in Communicable Diseases · All OCR AS-level Biology topics